Share Your Results — Tag us @skinsurgemd or email your before & after photos to be featured here.

Skip to product information
1 of 12

Skin SurgeMD

4% Syn-Ake 3x Peptide Wrinkle Serum | 10% Snap-8 | 20% Argireline | Anti-Wrinkle Serum

4% Syn-Ake 3x Peptide Wrinkle Serum | 10% Snap-8 | 20% Argireline | Anti-Wrinkle Serum

Regular price $24.99 USD
Regular price Sale price $24.99 USD
Unit price $2.50/ml
Sale Sold out
Shipping calculated at checkout.
Size
Quantity

Free USA shipping and 5% off on all orders over $100

📦 Shipping & Returns

Shipping:

Free USA shipping on all orders of $100+. All orders are shipped within 2 business days of payment. The free shipping carrier and service level are selected at our discretion.
Shipping-policy

Returns:

We offer 14-day full refunds, no questions asked, on opened, partially used products. This means you have 14 days after receiving your item to request a return. Return Policy




Wrinkle Prevention for Your 20s & Early 30s

Start preventing wrinkles before they start. Skin SurgeMD's Syn-Ake 3X Peptide Wrinkle Serum is a lightweight, triple-peptide formula clinically studied to visibly reduce forehead lines, crow's feet, and laugh lines — and keep them from deepening over time.

Formulated with 4% Syn-Ake, 10% Snap-8, and 20% Argireline in a deep-hydration hyaluronic acid base, this fast-absorbing serum is your daily defense against expression wrinkles—before they become permanent.

⭐ "This is the most advanced preventative wrinkle serum we've formulated — designed to work at the source of expression lines before they set in." Founder, Skin SurgeMD | Expert Peptide Formulator

🩷 Benefits

❓ Which Syn-Ake Serum Is Right for You?

We make three Syn-Ake serums, each formulated for a different stage of skin aging. 👉 Not sure which one is right for you? If you're in your 20s or early 30s and want to get ahead of wrinkles before they deepen, this is your serum.

✅ This Serum

Best For: 20s – Early 30s
Goal: Prevention + early lines
Syn-Ake Strength: 4% Syn-Ake
Intensity: Daily defense

💡 Who This Serum Is For

  • You're in your 20s or early 30s and want to target wrinkles before they set in
  • You're starting to notice early forehead lines, crow's feet, or laugh lines
  • Have wrinkles at 25
  • You spend extended time outdoors and want daily wrinkle defense
  • You want skin that stays smooth, plump, and youthful

🩷 Why Customers Love It

  • Relaxes forehead wrinkles from raising eyebrows
  • Softens crow's feet
  • Smooths laugh lines and other face stress lines
  • Helps keep fine lines and wrinkles from forming
  • Deep hydration + visible skin plump
  • Improves skin elasticity

📊 Clinical Results

🐍 4% Syn-Ake Peptide — Clinically studied to reduce forehead wrinkles by 52% over 28 days by relaxing expression muscle tension.

⚛ 10% Snap-8 (Acetyl Octapeptide-3) — Reduces crow's feet by up to 63% in 28 days. Targets wrinkles caused by repetitive facial movements.

🧪 20% Argireline (Acetyl Hexapeptide-8) — Reduces laugh line depth by 30% in 30 days. Works synergistically with Snap-8 for amplified smoothing.

🐚 20% Marine Collagen — Supports skin elasticity and firmness.

💦 3% Hyaluronic Acid — Deep hydration for visibly plumper skin.

🛡️ 1% Beta Glucan — Calms and strengthens the skin barrier.

💧 y-PGA (Polyglutamic Acid) — Holds up to 5,000x its weight in water. Gold standard in skin hydration.

🎁 What You Get

  • 10mL, 20mL, or 30mL of Syn-Ake 3x Peptide Wrinkle Serum
  • Buy the 15ml bottle and get an extra 5ml FREE — you'll receive 20ml total. Same price, more serum. While supplies last.
  • Max doses of Syn-Ake, Snap-8, Argireline, HA, and Marine Collagen
  • A free 1.0mm derma roller when you buy a 30mL bottle
  • Free shipping $100+ within the USA

Sizes: 10ml, 15ml (get 20ml), 30ml
Texture: Lightweight, fast-absorbing, non-comedogenic
Scent: Fragrance-free
Skin Types: All skin tones & types
Pro Tip: Use daily morning and evening for maximum results.

📖 How To Use

How to Use 4% Syn-Ake Serum

  1. Cleanse: Start with clean skin
  2. Apply: After cleanser, toner, and Vitamin C, morning and night, in the opposite direction of the wrinkle
  3. Pat gently: Tap serum into the forehead, around the eyes, and expression areas
  4. Moisturize: Follow with peptide cream or moisturizer. Finish with SPF in the morning.

**For best results, use twice daily and once weekly as a beauty treatment.

🧪 Full Ingredients

Deionized Water (Aqua), Glycerin, Sodium Hyaluronate (Hyaluronic Acid), Hydrolyzed Marine Collagen, Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake), Acetyl Octapeptide-3 (Snap-8), Acetyl Hexapeptide-8 (Argireline), Beta Glucan, Phenoxyethanol-Ethylhexylglycerin (Euxyl PE 9010), Tetrasodium EDTA, Polyglutamic Acid, Cichorium Intybus Extract (Chicory Root Extract).

⚠️ Storage & Safety

📦 Storage

  • Store in a cool, dry place.
  • Refrigeration is recommended but not required.
  • Keep the bottle tightly closed when not in use.

🗓️ Expiration

  • Unopened: 12 months
  • After opening: Use within 6 months

⚠️ Caution:

Use as directed. Avoid contact with eyes — flush with water if contact occurs. Discontinue use if redness or irritation develops. Keep out of reach of children. For external use only.

View full details
Best For:
Anti-wrinkle Firming Plumping Anti-aging Smoothing Hydrating Anti-dullness Moisturizing Lifting Pore tightening Brightening Repairing All skin types Aging Mature Dry Sensitive Combination Normal