Visibly Smoother Forehead Lines — Without Injectables
Syn-Ake is the closest thing skincare has to a topical muscle relaxer. Skin SurgeMD's 6% Syn-Ake Serum, Snake Venom Peptide Serum delivers this precision-smoothing neuropeptide at clinical concentration — paired with 1% GHK-CU, EGF, 30% Marine Collagen, and 3% Hyaluronic Acid — to visibly soften forehead lines, frown lines, laugh lines, and crow's feet with an elegant, controlled smoothing effect.
Lightweight. Fragrance-free. Absorbs cleanly under makeup. Works morning or night.
✅ What You'll See
- Visibly relaxed forehead wrinkles and frown lines
- Softer 11 lines and crow's feet
- Improved skin firmness and density
- Deeper hydration and a plumper, smoother surface
- Refined skin texture and barrier repair
- Results in 7 days with daily use
🧬 Which Syn-Ake Serum Is Right for You?
We make three Syn-Ake serums — each formulated for a different stage of skin aging. Here's how to choose:
|
Syn-Ake 3x Peptide Wrinkle Serum |
✅ This Serum |
EGF Multi-Growth Factor Serum |
| Best For |
20s – Early 30s |
30s – 40s |
40s+ |
| Goal |
Prevention + early lines |
Active wrinkle reduction |
Deep repair + regeneration |
| Syn-Ake Strength |
4% Syn-Ake |
6% Syn-Ake |
4% Syn-Ake + EGF + GHK-Cu |
| Intensity |
Lightweight daily defense |
Targeted correction |
Advanced repair |
👉 Not sure which one is right for you? If you're in your 30s or 40s and already seeing active wrinkles you want to visibly correct — this is your serum.
⚡ What Is Syn-Ake Peptide — And Why 6%?
Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate) is a biomimetic neuropeptide inspired by temple viper venom proteins. It works by mimicking the muscle-relaxing mechanism of snake venom — visibly reducing the depth and frequency of dynamic expression wrinkles without injections.
Clinically studied at 4% to reduce forehead wrinkles by 52% in 28 days. We deliver it at 6% — 50% above the studied dose — for maximum precision smoothing.
🧬 Supporting Ingredient Complex
- ⚛ 1% GHK-CU (Copper Tripeptide-1) — Improves skin tone, texture, and collagen production. Supports visible firming and barrier repair.
- 🌱 EGF (Epidermal Growth Factor) — Supports smooth, renewed, youthful-looking skin and accelerates surface repair.
- 🐚 30% Marine Collagen Peptides — Promotes elasticity and cushions the skin's surface.
- 💦 3% Hyaluronic Acid — Deep hydration and enhanced plumping for all skin types.
🎁 What You Get
- Available in 10mL, 15mL, and 30mL
-
FREE bonus 5mL when you buy 15mL — you receive 20mL total
-
FREE 1.0mm Derma Roller with every 30mL order — add it to your cart
- Free shipping on orders $100+ within the USA
- Packaged in small bottles to preserve peptide potency
💡 Perfect For
- Adults in their 30s and 40s with active forehead wrinkles, frown lines, 11 lines, laugh lines, or crow's feet
- Anyone who wants a targeted topical wrinkle remover — not just prevention
- Microneedling, derma roller, and derma pen routines
- Daytime use under makeup — lightweight, zero residue
- All skin tones & types — especially aging, dehydrated, or wrinkle-prone
📖 How To Use
Apply to clean skin after cleanser and toner, morning and night. Pat gently into foreheadthe , around eyes, and expression areas — moving in the reverse direction of the wrinkle.
As a treatment: Apply 5mL during or just after microneedling or derma rolling. Reapply on cleansed skin within 3 days post-treatment.
Texture: Lightweight, fast-absorbing gel-serum | Scent: Fragrance-free | Skin Types: All skin tones & types
Pro Tip: Pair with our Lazy Day Glow Pads and GHKcu Cream for a complete wrinkle-lifting routine.
🧪 Full Ingredient List
Deionized Water, Glycerin, Hyaluronic Acid, Marine Collagen, Syn-Ake Peptide, Copper Tripeptide-1 (GHK-CU), Epidermal Growth Factor (EGF), Tetrasodium EDTA, Chicory Root Extract, Euxyl PE 9010, Polyglutamic Acid.
📦 Storage: Store in a cool, dry place. Refrigeration recommended but not required.
⚠️ Caution: Avoid contact with eyes. Discontinue if irritation occurs. Keep out of reach of children.