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  • A 1 oz jar of Syn-Ake Multi-Peptide Anti-Wrinkle Cream by Skin SurgeMD, featuring a dark blue jar, black lid, and white label. A green circular badge in the top right corner reads 'FORMULATED IN THE USA' with an American flag map graphic.
  • A blue pump bottle of Syn-Ake Multi-Peptide Cream by Skin SurgeMD, presented on a white infographic background with text highlighting key ingredients 10% syn-ake, 10% snap-8, 5% collaxyl, 1% ceramides, EGF and skin benefits.
  • An informational graphic for Skin SurgeMD Triple-Action Barrier Shield, detailing three key ingredients: 1% Ceramides, 2% DL-Panthenol, and 15% Marine Collagen, with text explaining their benefits for skin repair, hydration, and protection.
  • An informational infographic for Skin Surgemd anti-wrinkle technology, featuring three circular diagrams labeled 10% Syn-Ake, 10% Snap-8, and 5% Collaxyl, with text detailing clinical results on forehead wrinkles, crow's feet and deep expression lines, fine lines and wrinkles.
  • Promotional graphic for a syn-ake peptide cream showing a close-up of a woman's face with dotted green lines pointing to specific wrinkles and skin areas, including forehead lines, glabellar lines, crow's feet, under eyes, nasolabial folds, marionette lines, jawline and neck sagging, and crepey skin.
  • A promotional graphic for Skin SurgeMD Syn-Ake Multi-Peptide Cream, showing a dark blue pump bottle with a black cap and white label, alongside marketing text and icons about clinical strength, COA-tested ingredients, no fillers, fragrance-free, cruelty free, made in the USA, and refrigerated freshness. Ice cubes are shown at the bottom right.
  • An infographic titled HOW TO USE syn-ake multi-peptide anti-wrinkle cream with morning and night sections showing five steps for skincare application, including cleanser, serum, cream, SPF, and EGF serum, with icons and brief instructions on a white background.
  • An infographic showing a 5-step anti-aging routine with blue and white skincare bottles and pump bottles, labeled Step 1 through Step 5 with product names and descriptions, on a white background with a green banner at the bottom.
  • A comparison infographic titled WHAT MAKES THIS Syn-Ake cream diFFERENT?' showing a table comparing other peptide serums versus Skin Surgemd Syn-Ake Cream, with checkmarks and icons highlighting differences in ingredients, hydration, cellular repair, peptide concentration, and storage.
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Skin SurgeMD

10% Syn-Ake Multi-Peptide Anti-Wrinkle Cream + 10% Snap-8 | Skin Barrier Protection

10% Syn-Ake Multi-Peptide Anti-Wrinkle Cream + 10% Snap-8 | Skin Barrier Protection

$44.99 USD
$44.99 USD
$44.99/ml
Sale Sold out
Shipping calculated at checkout.
Size

🧬 10% Syn-Ake Cream | Snake Venom Peptide | + 10% Snap-8 + Ceramides + EGF + 5% Collaxyl Peptide

Meet the ultimate intelligent hydrator engineered for mature, dry, normal, breakout-prone, sensitive, or post-treatment skin. Whether you are dealing with stubborn deep forehead wrinkles, static creases, or fine lines from years of expressive movement, this feather-light, cold-process Syn-Ake cream delivers an advanced complex of potent neuropeptides and signal peptides directly to the skin. Formulated as a high-performance anti-wrinkle day cream, it treats forehead lines, glabellar lines, smile lines, and smoker's lines all while restoring a damaged skin barrier with a zero-comedogenic lipid base.

🩷 Why Customers Love It

· Visible smoothing of forehead lines and crow's feet from raising eyebrows and squinting

· Plumping, hydrating serum that doesn't feel heavy or greasy

· Combines Syn-Ake, Snap-8, Collaxyl, Ceramide NP, and EGF to create a powerful topical lightweight gel-cream

· Signals natural cellular regeneration, firms loose skin, and improves overall skin elasticity.

· An advanced blend of 1% active ceramides, 2% DL-panthenol (pro-vitamin B5), and multi-depth hyaluronic acid helps repair the corneum, stop trans-epidermal water loss (TEWL), and calm active irritation.

· Helps minimize forehead wrinkles, crow's feet, fine lines, 11 lines, nasolabial folds, and marionette lines without triggering acne breakouts.

· High active peptide concentration, non-comedogenic, and acne-safe forehead wrinkle treatment

 

✅ Perfect For

· Improving forehead lines and crow's feet in 2-4 weeks

· Relaxing expression lines and dynamic wrinkles

· Hydrating dehydrated and crepey skin

· Repairing damaged skin barriers

· Users looking to visibly tighten and firm fine lines and wrinkles

· Users looking to immediately plump and smooth skin

· Oily or combination skin needing hydration without clogging

 

🔑 Key Ingredients & Why They Matter

· 🐍 10% Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate) – Snake venom-inspired peptide, clinically studied at 4% concentration of a 1% solution to reduce forehead wrinkles by 52% over 28 days. Visibly smooths forehead wrinkles by relaxing their appearance.

· ⚛ 10% Snap-8 (Acetyl Octapeptide-3) – When clinically tested at 10% concentration, it decreased crow's feet by up to 63% in 28 days.

· ⚛ 5% Collaxyl (Hexapeptide-9) – When clinically tested at 1.5% concentration, it decreased deep wrinkle depth and length on average by 68%, moderate wrinkle depth by 51%, and boosted collagen production over 100% in 30 days.

· 🌱 EGF (sh-Oligopeptide-1) — Wound, wrinkle, and sagging skin tissue rejuvenation

· ⛨ Ceramide NP – Prevents moisture loss, soothes, and protects skin barrier against environmental aggressors.

· 🐚 20% Marine Collagen – Supports skin elasticity and firmness

· 💦 3% Hyaluronic Acid – Deep hydration for plump skin

 

🎁 What You Get

** Free shipping within the USA for $100+

** 1oz, 2oz or 4oz bottle of Syn-Ake Cream

** Max doses of Syn-Ake, Snap-8, Collaxyl, EGF, HA, and Marine Collagen

Sizes Available: 1oz, 2oz, and 4oz

Texture: Lightweight, fast-absorbing cream

Scent: Fragrance-free

Skin Types: Normal, Dry, Mature, Sensitive, Oily

Pro Tip: Use twice daily for maximum visible results.

Formulated Without: Parabens, sulfates, phthalates, synthetic fragrance

 

📖 How to Use Syn-Ake Peptide Cream

Apply to clean skin after cleanser, toner, and serum in the morning and at night. A pea-to-nickel-sized amount is sufficient for the entire face.

 

🧪 Ingredients

Deionized Water (Aqua), Glycerin, Sodium Hyaluronate (Hyaluronic Acid), Hydrolyzed Marine Collagen, Caprylic/Capric Triglyceride, Octyldodecanol, Acrylate/Sodium Acryldimethyl-Taurate Copolymer, Isohexadecane, Polysorbate 80, Panthenol, Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake), Acetyl Octapeptide-3 (Snap-8), Polypeptide Hexapeptide-9 (Collaxyl), sh-Oligopeptide-1 (EGF), Ceramide, Fatty Acids, Cholesterol, Cholesteryl Esters, Polyglutamic Acid, Beta Glucan, Tocopherol (Vitamin E), Tetrasodium EDTA, Phenoxyethanol-Ethylhexylglycerin (Euxyl PE 9010).

 

📦 Storage

  • Store at room temperature
  • Avoid prolonged heat exposure
  • Keep bottle tightly closed when not in use

🗓️ Expiration

· Unopened: 24 months

· After opening: Use within 12 months

 

⚠️ Caution

Use as directed and avoid contact with eyes. If the product gets into the eyes, flush with water. Discontinue use if redness or irritation occurs. Keep out of reach of children. For external use only. Patch test before first use.

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Best For:
Anti-wrinkle Firming Plumping Anti-aging Smoothing Hydrating Anti-dullness Moisturizing Lifting Pore tightening Brightening Repairing Soothing Protection All skin types Aging Mature Dry Sensitive Combination Normal Oily