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  • A 1 oz jar of Syn-Ake Multi-Peptide Anti-Wrinkle Cream by Skin SurgeMD, featuring a dark blue jar, black lid, and white label. A green circular badge in the top right corner reads 'FORMULATED IN THE USA' with an American flag map graphic.
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  • Promotional graphic for a syn-ake peptide cream showing a close-up of a woman's face with dotted green lines pointing to specific wrinkles and skin areas, including forehead lines, glabellar lines, crow's feet, under eyes, nasolabial folds, marionette lines, jawline and neck sagging, and crepey skin.
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Skin SurgeMD

10% Syn-Ake Multi-Peptide Anti-Wrinkle Cream + 10% Snap-8 | Skin Barrier Protection

10% Syn-Ake Multi-Peptide Anti-Wrinkle Cream + 10% Snap-8 | Skin Barrier Protection

$44.99 USD
$44.99 USD
$44.99/ml
Sale Sold out
Shipping calculated at checkout.
Size

Free USA shipping and 5% off on all orders over $100

📦 Shipping & Returns

Shipping:

Free USA shipping on all orders of $100+. All orders are shipped within 2 business days of payment. The free shipping carrier and service level are selected at our discretion.
Shipping-policy

Returns:

We offer 14-day full refunds, no questions asked, on opened, partially used products. This means you have 14 days after receiving your item to request a return. Return Policy




🧬 10% Syn-Ake Cream | Snake Venom Peptide | + 10% Snap-8 + Ceramides + EGF + 5% Collaxyl Peptide

Meet the ultimate intelligent hydrator engineered for mature, dry, normal, breakout-prone, sensitive, or post-treatment skin. Whether you are dealing with stubborn deep forehead wrinkles, static creases, or fine lines from years of expressive movement, this feather-light, cold-process Syn-Ake cream delivers an advanced complex of potent neuropeptides and signal peptides directly to the skin. Formulated as a high-performance anti-wrinkle day cream, it treats forehead lines, glabellar lines, smile lines, and smoker's lines all while restoring a damaged skin barrier with a zero-comedogenic lipid base.

🩷 Benefits

🩷 Why Customers Love It

  • Visible smoothing of forehead lines and crow's feet from raising eyebrows and squinting
  • Plumping, hydrating cream that doesn't feel heavy or greasy
  • Combines Syn-Ake, Snap-8, Collaxyl, Ceramide NP, and EGF to create a powerful, silky-smooth, lightweight topical gel-cream
  • Signals natural cellular regeneration, firms loose skin, and improves overall skin elasticity.
  • An advanced blend of 1% active ceramides, 2% DL-panthenol (pro-vitamin B5), and multi-depth hyaluronic acid helps repair the corneum, stop trans-epidermal water loss (TEWL), and calm active irritation.
  • Helps minimize forehead wrinkles, crow's feet, fine lines, 11 lines, nasolabial folds, and marionette lines without triggering acne breakouts.
  • High active peptide concentration, non-comedogenic, and acne-safe forehead wrinkle treatment

✅ Syn-Ake Cream is Perfect For

  • Improving forehead lines and crow's feet in 2-4 weeks
  • Relaxing expression lines and dynamic wrinkles
  • Hydrating dehydrated and crepey skin
  • Repairing damaged skin barriers
  • Users looking to visibly tighten and firm fine lines and wrinkles
  • Users looking to immediately plump and smooth skin
  • Oily or combination skin needing hydration without clogging

 

📊 Clinical Results

🔑 Key Ingredients & Why They Matter

🐍 10% Syn-Ake (Dipeptide Diaminobutyroyl Benzylamide Diacetate) – Snake venom-inspired peptide, clinically studied at a 4% concentration of a 1% active solution to reduce forehead wrinkles by 52% over 28 days. Visibly smooths forehead wrinkles by relaxing their appearance.

⚛ 10% Snap-8 (Acetyl Octapeptide-3) – When clinically tested at 10% concentration, it decreased crow's feet by up to 63% in 28 days.

⚛ 5% Collaxyl (Hexapeptide-9) – When clinically tested at 1.5% concentration, it decreased deep wrinkle depth and length on average by 68%, moderate wrinkle depth by 51%, and boosted collagen production by over 100% in 30 days.

🌱 EGF (sh-Oligopeptide-1) — Wound, wrinkle, and sagging skin tissue rejuvenation

⛨ Ceramide NP – Prevents moisture loss, soothes, and protects the skin barrier against environmental aggressors.

🐚 20% Marine Collagen – Supports skin elasticity and firmness

💦 3% Hyaluronic Acid – Deep hydration for plump skin

🎁 What You Get

  • 1oz, 2oz or 4oz bottle of Syn-Ake Cream
  • Max doses of Syn-Ake, Snap-8, Collaxyl, EGF, HA, and Marine Collagen
  • Free shipping within the USA for $100+

Sizes Available: 1oz, 2oz, and 4oz
Texture: Lightweight, fast-absorbing cream
Scent: Fragrance-free
Skin Types: Normal, Dry, Mature
Pro Tip: Use daily for maximum visible results.
Formulated Without: Parabens, sulfates, phthalates, synthetic fragrance

📖 How To Use

How to Use Syn-Ake Peptide Cream

  1. Cleanse: Start with clean skin
  2. Apply: After cleanser, toner, and serum, in the morning and at night
  3. Moisturize: Rub a pea-to-nickel-sized amount onto the face, neck, and chest

🧪 Full Ingredients

Deionized Water (Aqua), Glycerin, Sodium Hyaluronate (Hyaluronic Acid), Hydrolyzed Marine Collagen, Caprylic/Capric Triglyceride, Octyldodecanol, Acrylate/Sodium Acryldimethyl-Taurate Copolymer, Isohexadecane, Polysorbate 80, Panthenol, Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-Ake), Acetyl Octapeptide-3 (Snap-8), Polypeptide Hexapeptide-9 (Collaxyl), sh-Oligopeptide-1 (EGF), Ceramide, Fatty Acids, Cholesterol, Cholesteryl Esters, Polyglutamic Acid, Beta Glucan, Tocopherol (Vitamin E), Phenoxyethanol-Ethylhexylglycerin (Euxyl PE 9010).

⚠️ Storage & Safety

📦 Storage:

  • Store at room temperature.
  • Avoid prolonged heat exposure.
  • Keep the bottle/jar tightly closed when not in use. 

🗓️ Expiration:

  • Unopened: 24 months
  • After opening: Use within 12 months

🚫 Free From

  • Parabens
  • Phthalates
  • Formaldehyde donors
  • Sulfates
  • Synthetic Fragrance

⚠️Caution:

Use as directed and avoid contact with eyes. If the product gets into the eyes, flush with water. Discontinue use if redness or irritation occurs. Keep out of reach of children. For external use only. Patch test before first use.

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Best For:
Anti-wrinkle Firming Plumping Anti-aging Smoothing Hydrating Anti-dullness Moisturizing Lifting Pore tightening Brightening Repairing Soothing Protection Illuminating Tightening Anti-scars Softening All skin types Aging Mature Dry Sensitive Combination Normal Oily